THE GLOBAL PROBLEM OF ANTIBIOTIC RESISTANCE MORTALITY AND BACTERIOPHAGES AS A SOLUTION
Keywords:
Bacteriophages, multidrug resistance, infectious complications, Sextafag, antibiotics.Abstract
In clinical practice, we hear more and more often about the decrease or lack of sensitivity to antibiotic therapy, which is largely due to the uncontrolled use of drugs and, accordingly, spurring the natural mechanisms of bacteria to develop defenses. Synthesis and development of new groups of antibiotics, as the dynamics of resistance development shows, is a temporary solution to the problem. Thus, a vicious circle is formed, which will lead to a crisis in the fight against bacteria. This article analyzes studies aimed at investigating the use of bacteriophages to find and improve the results of treatment of patients with antibiotic-resistant pathologies from different fields of medicine.
References
L Murray C.J, Ikuta K.S., Sharara F., Swetschinski L., Aguilar G.R., et al. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis. VOLUME 399, ISSUE 10325, P629-655, FEBRUARY 12, 2022. Authia Gray DOI: https://doi.org/10.1016/S0140-6736(21)02724-0 © 2021 The Author(s). Published by Elsevier Ltd.
Laxminarayan R., Duse A., Wattal C., Zaidi A.K., Wertheim H.F., Sumpradit N., et al. Antibiotic resistance-the need for global solutions. Lancet Infect Dis. 2013;13:1057-1098. DOI: 10.1016/S1473-3099(13)70318-9
Luepke K.H., Suda K.J., Boucher H., Russo R.L., Bonney M.W., Hunt T.D., Mohr J.F.. Past, present, and future of antibacterial economics: increasing bacterial resistance, limited antibiotic pipeline, and societal implications. Pharmacotherapy. 2017;37:71-84. DOI: 10.1002/ phar.1868
Sulakvelidze A., Alavidze Z., Morris J.G.. Bacteriophage therapy. Antimicrob Agents Chemother. 2001;45:649-659. DOI: 10.1128/AAC.45.3.649-659.2001
Manrique P., Bolduc B. , Walk S.T., J. van der Oost, W.M. de Vos, M.J. Young; Healthy human gut phageome; Proc Natl Acad Sci U S A, 113 (2016), pp. 10400-10405
D.R. Roach, D.M. Donovan, Antimicrobial bacteriophage-derived proteins and therapeutic applications, Bacteriophage, 5 (2015), Article e1062590
C.I. Coleman, B. Limone, D.M. Sobieraj, et al. Dosing frequency and medication adherence in chronic disease; J Manage Care Pharm, 18 (2012), pp. 527-539
Fedorov E.A., Kretien S.O., Samokhin A.G., Tikunova N.V., Korytkin A.A., Pavlov V.V.. Short-term results of treatment of staphylococcal periprosthetic hip joint infection with combined antibiotics and bacteriophages treatment. Actabiomedicascientifica. 2021; 6(4): 50-63. doi: 10.29413/ABS.2021-6.4.5
Jault P., Leclerc T., Jennes S., Pirnay J.P., Que Y.A., Resch G., et al. Efficacy and tolerability of a cocktail of bacteriophages to treat burn wounds infected by Pseudomonas aeruginosa (PhagoBurn): a randomised, controlled, double-blind phase 1/2 trial. Lancet Infect Dis. 2019;19(1):35-45. DOI: 10.1016/S1473-3099(18)30482-1
Буданов П. В., Новахова Ж. Д., Чурганова А. А. Альтернатива антибактериальной терапии в акушерстве и гинекологии //РМЖ. Мать и дитя. – 2015. – №. 1. – С. 14-18.;
Паршин Д.С. , Топчиев М.А., Пятаков С.Н. , Бадма-Горяев О. В. , Куприянов А. В., Алибеков Р.С.; РЕЗУЛЬТАТЫ ФАГОТЕРАПИИ ИНФЕКЦИОННЫХ ОСЛОЖНЕНИЙ В НЕОТЛОЖНОЙ АБДОМИНАЛЬНОЙ ХИРУРГИИ; УДК: 617.55-089-06:576.858.9 DOI: 10.37279/2070-8092-2022-25-2-72-80;
Байтилеуов Т. А., Якупбаева К. Х., Садыков Н. К. Антибактериальная терапия при лечении инфицированного панкреонекроза //Вестник хирургии Казахстана. – 2010. – №. 2 (22). - С. 14
Rubalskii E., Ruemke S., Salmoukas C., Erin C. Boyle, Warnecke G., Todorache I. et al. Bacteriophage therapy for critical infections related to cardiothoracic surgery //Antibiotics. – 2020. – Т. 9. – №. 5. – С. 232.
Салмина Т. А., Цыгипало А. И., Шкода А. С. Опыт применения пиобактериофага поливалентного очищенного для лечения гнойных ран при длительном и неэффективном лечении антибактериальными препаратами //Трудный пациент. – 2016. – Т. 14. – №. 10-11. – С. 23-29.
Байматов Р. А., Нурузова З. А. Видовая характеристика и антибиотикорезистентность возбудителей гнойно-воспалительных заболеваний //Re-health journal. – 2019. – №. 3. – С. 115-124.
Ташханова Д. Я., Нурматова Н. Ф. Анализ распространения антибиотикоустойчивых бактерий в Республике Узбекистан //Педиатр. – 2017. – Т. 8. – №. S.
Luong T., Salabarria A. C., Roach D. R. Phage therapy in the resistance era: where do we stand and where are we going? //Clinical therapeutics. – 2020. – Т. 42. – №. 9. – С. 1659-1680. https://doi.org/10.1016/j.clinthera.2020.07.014