CHANGE OF BIOCHEMICAL INDICATORS IN THE NEPROTIC FORM OF CHRONIC GLOMERULONEPHRITIS IN CHILDREN AND THEIR RECOVERY
Abstract
Nephropathies are common in pediatric practice and make up 5-7% of common diseases. Chronic glomerulonephritis (CG) is one of the diseases specific to the Central Asian region, and in most cases, it is one of the causes of end-stage renal failure, along with congenital and acquired nephropathies [3,7,8]. According to the data of M.S. Ignatova (2003-2010), 50% of patients with glomerulonephritis have nephrotic syndrome (NS) [1,5]. The experimental and clinical studies of the following years made it possible to analyze the pathogenesis of SG more deeply, that is, as a result of this disease, it was shown that pathological changes develop in many tissues and organs. According to some authors, liver dysfunction leads to changes in metabolism [5]. It should be said that SG, especially its nephrotic form, is accompanied by lipid metabolism disorders. They are mainly characterized by hypercholesterolemia, hypertriglyceridemia, and this occurs due to a violation of lipoprotein metabolism in the liver [2,4,9].
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